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Article

Association study between vitiligo and autoimmune-related genes CYP27B1, REL, TNFAIP3, IL2 and IL21.

Experimental dermatology - 1 Jun 2020

Martins Laysa Toschi, Frigeri Henrique Ravanhol, de Castro Caio Cesar Silva, Mira Marcelo Távora

Abstract excerpt

The aetiology of vitiligo has not been fully elucidated, and several hypotheses have been investigated; among them, the most explored assumes an autoimmune basis for the disease. Supporting this hypothesis is the frequent co-occurrence of autoimmune diseases with vitiligo. In addition, various genetic loci associated with vitiligo harbour key immune response genes. Our general hypothesis is that...

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PMID: 32282963
DOI: 10.1111/exd.14100

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