Protein–protein interaction network with machine learning models and multiomics data reveal potential neurodegenerative disease-related proteins

Abstract excerpt

Research of protein-protein interaction in several model organisms is accumulating since the development of high-throughput experimental technologies and computational methods. The protein-protein interaction network (PPIN) is able to examine biological processes in a systematic manner and has already been used to predict potential disease-related proteins or drug targets. Based on the topological characteristics...

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