Article
Neurometabolic effects of sweetened solution intake during adolescence related to depressive-like phenotype in rats.
Nutrition (Burbank, Los Angeles County, Calif.) - 1 Jan 2000
Arcego Danusa Mar, Olivo Laura Bem, Moraes Rafael Oliveira, Garcia Emily Dos Santos, Silveira Ana Caroline, Krolow Rachel, Couto-Pereira Natividade de Sá, Lampert Carine, Toniazzo Ana Paula, Nicola Fabrício do Couto, Sanches Eduardo Farias, Aristimunha Dirceu, Hoppe Juliana Bender, Klein Caroline Peres, Fontella Fernanda Urruth, Almeida Roberto Farina, Gamaro Giovana Duzzo, Fróes Fernanda Carolina Telles da Silva, Leite Marina Concli, Netto Carlos Alexandre, Zancan Denise Maria, Dalmaz Carla
Abstract excerpt
OBJECTIVE: Exposure to artificial sweeteners, such as aspartame, during childhood and adolescence has been increasing in recent years. However, the safe use of aspartame has been questioned owing to its potentially harmful effects on the developing brain. The aim of this study was to test whether the chronic consumption of aspartame during adolescence leads to a depressive-like phenotype and to investigate the...
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