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Article

Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2020

Googins Matthew R, Woghiren-Afegbua Aigbirhemwen O, Calderon Michael, St Croix Claudette M, Kiselyov Kirill I, VanDemark Andrew P

Abstract excerpt

Mutations in ganglioside-induced differentiation-associated protein 1 (GDAP1) alter mitochondrial morphology and result in several subtypes of the inherited peripheral neuropathy Charcot-Marie-Tooth disease; however, the mechanism by which GDAP1 functions has remained elusive. GDAP1 contains primary sequence homology to the GST superfamily; however, the question of whether GDAP1 is an active GST has not been...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 32274853
DOI: 10.1096/fj.202000110R
PMCID: PMC9394736

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Structural and functional divergence of GDAP1 from the glutathione S-transferase superfamily.PMID 32274853Read ↗

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