Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

M16-Type Metallopeptidases Are Involved in Virulence for Invasiveness and Diffusion of Leptospira interrogans and Transmission of Leptospirosis.

The Journal of infectious diseases - 17 Aug 2020

Ge Yu-Mei, Sun Ai-Hua, Ojcius David M, Li Shi-Jun, Hu Wei-Lin, Lin Xu'ai, Yan Jie

Abstract excerpt

BACKGROUND: Leptospirosis is a global zoonotic infectious disease caused by Leptospira interrogans. The pathogen rapidly invades into hosts and diffuses from bloodstream into internal organs and excretes from urine to cause transmission of leptospirosis. However, the mechanism of leptospiral invasiveness remains poorly understood. METHODS: Proteolytic activity of M16-type metallopeptidases (Lep-MP1/2/3) of L....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bacterial Load
Share to Biopsy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cricetinae

Share to Leptospirosis

Share to Metalloproteases

Share to Proteolysis

Share to Rabbits

Share to Virulence Factors

Source

Identifiers

PMID: 32274497
DOI: 10.1093/infdis/jiaa176

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

M16-Type Metallopeptidases Are Involved in Virulence for Invasiveness and Diffusion of Leptospira interrogans and Transmission of Leptospirosis.PMID 32274497Read ↗

Identification of Collagenase as a Critical Virulence Factor for Invasiveness and Transmission of Pathogenic Leptospira SpeciesSemantic proximity Read ↗

Pathogenic, diagnostic and vaccine potential of leptospiral outer membrane proteins (OMPs)Semantic proximity Read ↗

Transcriptional Responses of Leptospira interrogans to Host Innate Immunity: Significant Changes in Metabolism, Oxygen Tolerance, and Outer MembraneSemantic proximity Read ↗

Peptidoglycan Mediates Loa22 and Toll-like Receptor 2 Interactions in Pathogenic <i>Leptospira</i>Semantic proximity Read ↗

Unique physiological and pathogenic features of Leptospira interrogans revealed by whole-genome sequencingSemantic proximity Read ↗

<i>In Vivo</i> Dual RNA-Seq uncovers key toxin-like effectors of epithelial barrier disruption and tissue colonization by an extracellular bacterial pathogenSemantic proximity Read ↗

[Immune-functional epitopes and inflammation-inducing effects of the major outer envelope proteins of Leptospira interrogans].Semantic proximity Read ↗

Evaluation of LipL32 and LigA/LigB Knockdown Mutants in Leptospira interrogans Serovar Copenhageni: Impacts to Proteome and VirulenceSemantic proximity Read ↗

Proteome Analysis of Leptospira interrogans Virulent StrainSemantic proximity Read ↗

Leptospiral outer membrane protein LMB216 is involved in enhancement of phagocytic uptake by macrophagesSemantic proximity Read ↗

Lsa63, a newly identified surface protein of Leptospira interrogans binds laminin and collagen IVSemantic proximity Read ↗

The oxidative stress response of pathogenic Leptospira is controlled by two peroxide stress regulators which putatively cooperate in controlling virulence.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.