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Article

Fungal Kti12 proteins display unusual linker regions and unique ATPase p-loops.

Current genetics - 1 Aug 2020

Krutyhołowa Rościsław, Reinhardt-Tews Annekathrin, Chramiec-Głąbik Andrzej, Breunig Karin D, Glatt Sebastian

Abstract excerpt

Kti12 (Kluyveromyces lactis toxin insensitive 12) is an evolutionary highly conserved ATPase, crucial for the tRNA-modification activity of the eukaryotic Elongator complex. The protein consists of an N-terminal ATPase and a C-terminal tRNA-binding domain, which are connected by a flexible linker. The precise role of the linker region and its involvement in the communication between the two domains and their...

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Identifiers

PMID: 32236652
DOI: 10.1007/s00294-020-01070-2
PMCID: PMC7363723

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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