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Article

The rs11755527 polymorphism in the BACH2 gene and type 1 diabetes mellitus: case control study in a Brazilian population.

Archives of endocrinology and metabolism - 1 Apr 2020

Dieter Cristine, Lemos Natália Emerim, Dorfman Luiza Emy, Duarte Guilherme Coutinho Kullmann, Assmann Taís Silveira, Crispim Daisy

Abstract excerpt

Objective Type 1 diabetes mellitus (T1DM) is an autoimmune disorder caused by a complex interaction between environmental and genetic risk factors. BTB domain and CNC homolog 2 (BACH2) gene encodes a transcription factor that acts on the differentiation and formation of B and T lymphocytes. BACH2 is also involved in the suppression of apoptosis and inflammation in pancreatic beta-cells, indicating a role for it...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32236312
DOI: 10.20945/2359-3997000000214
PMCID: PMC10118942

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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