Genetic Determinants of Inherited Cardiac Arrhythmias.

Abstract excerpt

Inherited cardiac arrhythmias are a major cause of sudden cardiac death in individuals without structural heart disease. These conditions are primarily genetic, resulting from pathogenic variants affecting cardiac ion channels, calcium-handling proteins, intercellular junctions, and transcriptional regulators. While research has traditionally focused on ventricular syndromes such as long QT syndrome, Brugada...

Topics

• Humans
• Genetic Predisposition to Disease
• Arrhythmias, Cardiac
• Death, Sudden, Cardiac
• Phenotype
• Risk Factors
• Heredity