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Article

Meta-Analysis of Associations Between Hypothalamic-Pituitary-Adrenal Axis Genes and Risk of Posttraumatic Stress Disorder.

Journal of traumatic stress - 1 Oct 2020

Sheerin Christina M, Lind Mackenzie J, Bountress Kaitlin E, Marraccini Marisa E, Amstadter Ananda B, Bacanu Silviu-Alin, Nugent Nicole R

Abstract excerpt

The hypothalamic-pituitary-adrenal (HPA) axis has been of interest in attempts to identify genetic vulnerability for posttraumatic stress disorder (PTSD). Although numerous HPA-axis genes have been implicated in candidate gene studies, the findings are mixed and interpretation is limited by study design and methodological inconsistencies. To address these inconsistencies in the PTSD candidate gene literature, we...

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Identifiers

PMID: 32216170
DOI: 10.1002/jts.22484
PMCID: PMC7529653

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