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Article

Evaluation of single nucleotide polymorphisms in 6 candidate genes and carotid intima-media thickness in community-dwelling residents.

PloS one - 1 Jan 2020

Wu Fang-Yang, Li Chia-Ing, Liao Li-Na, Liu Chiu-Shong, Lin Wen-Yuan, Lin Chih-Hsueh, Yang Chuan-Wei, Li Tsai-Chung, Lin Cheng-Chieh

Abstract excerpt

Evidence suggests the existence of association between a large panel of modifiable biomarkers representing inflammation, coagulation, paraoxonase, and endothelial activation pathways and carotid atherosclerosis. Thus, this study investigated whether CRP, FGA, FGB, FGG, PON1, and EDNRA gene variants affected plasma hs-CRP, fibrinogen levels, and thickness of carotid intima media thickness (IMT). Nineteen...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 32214403
DOI: 10.1371/journal.pone.0230715
PMCID: PMC7098559

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