Article
Novel NLRC4-ALK and EML4-ALK double fusion mutations in a lung adenocarcinoma patient: A case report.
Thoracic cancer - 1 Jun 2020
Wu Xueqian, Wang Weiya, Zou Bingwen, Li Yanying, Yang Xiaojuan, Liu Ning, Ma Qizhi, Zhang Xiaoxuan, Wang Yongsheng, Li Dan
Abstract excerpt
Anaplastic lymphoma kinase (ALK) rearrangements have been reported in 5% to 6% of non-small cell lung cancer (NSCLC) patients. However, the concurrent existence of two ALK fusions within the same patient have rarely previously been reported. Moreover, considering the diversities of ALK mutations, it is necessary to evaluate the response of both double and new types of ALK fusions to ALK-tyrosine kinase inhibitors...
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