Article
Notch3: from subtle structural differences to functional diversity.
Oncogene - 1 Sept 2008
Bellavia D, Checquolo S, Campese A F, Felli M P, Gulino A, Screpanti I
Abstract excerpt
The Notch3 gene was identified, at the beginning of 90s, as the third mammalian Notch and was initially reported as being expressed in proliferating neuroepithelium. Since then, increasing evidence has demonstrated a number of structural and functional differences between Notch3 and both Notch1 and Notch2, which exhibit the highest structural similarity among the four mammalian Notch receptors. Possibly due to...
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