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Article

Pharmacogenomic response of low dose haloperidol in critically ill adults with delirium.

Journal of critical care - 1 Jun 2020

Trogrlić Zoran, van der Jagt Mathieu, Osse Robert Jan, Devlin John W, Nieboer Daan, Koch Birgit C P, van Schaik Ron H N, Hunfeld Nicole G M

Abstract excerpt

PURPOSE: To characterize the pharmacogenomic response of low-dose haloperidol for delirium treatment in critically ill adults. MATERIALS AND METHODS: Single-center, pilot study of a convenience sample of ICU adults with delirium treated with low-dose IV haloperidol. Patients were evaluated for delirium with the ICDSC every 8 h. Serum haloperidol concentrations were collected on ICU days 2-6, CYP2D6 and CYP3A4...

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Identifiers

PMID: 32208328
DOI: 10.1016/j.jcrc.2020.03.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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