Article
Assessing the virulence of Cryptococcus neoformans causing meningitis in HIV infected and uninfected patients in Vietnam.
Medical mycology - 10 Nov 2020
Thanh Lam Tuan, Toffaletti Dena L, Tenor Jennifer L, Giamberardino Charles, Sempowski Gregory D, Asfaw Yohannes, Phan Hai Trieu, Van Duong Anh, Trinh Nguyen Mai, Thwaites Guy E, Ashton Philip M, Chau Nguyen Va Vinh, Baker Stephen G, Perfect John R, Day Jeremy N
Abstract excerpt
We previously observed a substantial burden of cryptococcal meningitis in Vietnam atypically arising in individuals who are uninfected with human immunodeficiency virus (HIV). This disease was associated with a single genotype of Cryptococcus neoformans (sequence type [ST]5), which was significan...
Topics
- AIDS-Related Opportunistic Infections
- Animals
- Colony Count, Microbial
- Cryptococcus neoformans
- Cytokines
- Female
- Fungal Capsules
- Genotype
- Humans
- Immunocompetence
- Lung
- Male
- Meningitis, Cryptococcal