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Article

Population diversity and virulence characteristics of Cryptococcus neoformans/C. gattii species complexes isolated during the pre-HIV-pandemic era.

PLoS neglected tropical diseases - 1 Oct 2020

Pharkjaksu Sujiraphong, Kwon-Chung Kyung J, Bennett John E, Ngamskulrungroj Popchai

Abstract excerpt

Cryptococcosis has become a major global health problem since the advent of the HIV pandemic in 1980s. Although its molecular epidemiology is well-defined, using isolates recovered since then, no pre-HIV-pandemic era epidemiological data exist. We conducted a molecular epidemiological study using 228 isolates of the C. neoformans/C. gattii species complexes isolated before 1975. Genotypes were determined by URA5...

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Identifiers

PMID: 33017391
DOI: 10.1371/journal.pntd.0008651
PMCID: PMC7535028

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