Article
Comparative genomics of Cryptococcus neoformans var. grubii associated with meningitis in HIV infected and uninfected patients in Vietnam.
PLoS neglected tropical diseases - 1 Jun 2017
Day Jeremy N, Qihui Seet, Thanh Lam Tuan, Trieu Phan Hai, Van Anh Duong, Thu Nha Hoang, Chau Tran Thi Hong, Lan Nguyen P H, Chau Nguyen Van Vinh, Ashton Philip M, Thwaites Guy E, Boni Maciej F, Wolbers Marcel, Nagarajan Niranjan, Tan Patrick B O, Baker Stephen
Abstract excerpt
The vast burden of cryptococcal meningitis occurs in immunosuppressed patients, driven by HIV, and is caused by Cryptococcus neoformans var. grubii. We previously reported cryptococcal meningitis in Vietnam arising atypically in HIV uninfected, apparently immunocompetent patients, caused by a sin...
Topics
- Cryptococcus neoformans
- Genetic Variation
- Genome, Fungal
- Genomics
- HIV Infections
- Host Specificity
- Humans
- Meningitis, Cryptococcal
- Multilocus Sequence Typing
- Mycological Typing Techniques
- Vietnam