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Article

Targeted Sequencing Improves DIPSS-Plus Prognostic Scoring in Myelofibrosis Patients Undergoing Allogeneic Transplantation.

Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 Jul 2020

Stevens Emily A, Jenkins Isaac C, Beppu Lan W, Zhang Qing, Salit Rachel, Loeb Keith R, Deeg H Joachim, Radich Jerald P

Abstract excerpt

Primary myelofibrosis (MF) and secondary MF developing after polycythemia vera or essential thrombocythemia are clonal disorders of hematopoiesis. Currently the sole therapy offering the potential of cure is hematopoietic cell transplantation (HCT). Several risk classification systems including clinical, hematologic, and mutational parameters have been proposed. We analyzed the mutational landscape in addition to...

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PMID: 32194289
DOI: 10.1016/j.bbmt.2020.03.007

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