Article
CIViCpy: A Python Software Development and Analysis Toolkit for the CIViC Knowledgebase.
JCO clinical cancer informatics - 1 Mar 2020
Wagner Alex H, Kiwala Susanna, Coffman Adam C, McMichael Joshua F, Cotto Kelsy C, Mooney Thomas B, Barnell Erica K, Krysiak Kilannin, Danos Arpad M, Walker Jason, Griffith Obi L, Griffith Malachi
Abstract excerpt
PURPOSE: Precision oncology depends on the matching of tumor variants to relevant knowledge describing the clinical significance of those variants. We recently developed the Clinical Interpretations for Variants in Cancer (CIViC; civicdb.org) crowd-sourced, expert-moderated, and open-access knowledgebase. CIViC provides a structured framework for evaluating genomic variants of various types (eg, fusions,...
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