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Article

Executive function after risk-reducing salpingo-oophorectomy in BRCA1 and BRCA2 mutation carriers: does current mood and early life adversity matter?

Menopause (New York, N.Y.) - 1 Jul 2020

Shanmugan Sheila, Sammel Mary D, Loughead James, Ruparel Kosha, Gur Ruben C, Brown Thomas E, Faust Jessica, Domchek Susan, Epperson C Neill

Abstract excerpt

OBJECTIVE: Despite the fact that negative mood and executive dysfunction are common after risk-reducing salpingo-oophorectomy (RRSO), occurring in up to a third of women, little is known about risk factors predicting these negative outcomes. Adverse childhood experiences (ACE) predict poorer health in adulthood and may be a risk factor for negative outcomes after RRSO. Given the complex relationship between early...

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Identifiers

PMID: 32187134
DOI: 10.1097/GME.0000000000001535
PMCID: PMC7473450

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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