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Article

Suppression of a Subset of Interferon-Induced Genes by Human Papillomavirus Type 16 E7 via a Cyclin Dependent Kinase 8-Dependent Mechanism.

Viruses - 13 Mar 2020

Rice Sadie, Kim Seong-Man, Rodriguez Cynthia, Songock William, Raikhy Gaurav, Lopez Rebecca, Henderson Lauren, Yusufji Arjun, Bodily Jason

Abstract excerpt

Persistent infection by human papillomaviruses (HPVs), small, double-stranded DNA viruses that infect keratinocytes of the squamous epithelia, can lead to the development of cervical and other cancers. The viral oncoprotein E7 contributes to viral persistence in part by regulating host gene expression through binding host transcriptional regulators, although mechanisms responsible for E7-mediated transcriptional...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32183180
DOI: 10.3390/v12030311
PMCID: PMC7150855

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