Article
[Molecular basis of hereditary cancers].
Magyar onkologia - 17 Mar 2020
Tímár József
Abstract excerpt
Cancer susceptibility but not specific cancer types can be inherited. This susceptibility(ies) is due to inherited germline mutations of key genes of the controllers of genome integrity, translational control, the cell cycle regulation or even the tumor vascularization. Cancer susceptibility can be manifested in various forms of specific syndromes, each associated with different alterations of genes. Most of...
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