Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gene therapy and genome editing for primary immunodeficiency diseases

30 Jul 2019

Abstract excerpt

In past two decades the gene therapy using genetic modified autologous hematopoietic stem cells (HSCs) transduced with the viral vector has become a promising alternative option for treating primary immunodeficiency diseases (PIDs). Despite of some pitfalls at early stage clinical trials, the field of gene therapy has advanced significantly in the last decade with improvements in viral vector safety, preparatory...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CRISPR and Genetic Engineering
Share to Viral Infections and Immunology Research
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32181274
DOI: 10.1016/j.gendis.2019.07.007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gene therapy and genome editing for primary immunodeficiency diseasesPMID 32181274Read ↗

Gene therapy for PIDs: Progress, pitfalls and prospectsSemantic proximity Read ↗

Gene therapy for primary immunodeficiencySemantic proximity Read ↗

Gene therapy for primary immunodeficienciesSemantic proximity Read ↗

Gene Therapy for Primary ImmunodeficienciesSemantic proximity Read ↗

Clinical Applications of Gene Therapy for Primary ImmunodeficienciesSemantic proximity Read ↗

Gene Editing for the Treatment of Primary Immunodeficiency DiseasesSemantic proximity Read ↗

Evolving Gene Therapy in Primary ImmunodeficiencySemantic proximity Read ↗

Viral-based gene therapy clinical trials for immune deficiencies and blood disorders from 2013 until 2023 - an overviewSemantic proximity Read ↗

Genome-edited adult stem cells: Next-generation advanced therapy medicinal productsSemantic proximity Read ↗

Concise Review: Lessons Learned From Clinical Trials of Gene Therapy in Monogenic Immunodeficiency DiseasesSemantic proximity Read ↗

Gene Therapy for X-Linked Severe Combined Immunodeficiency: Where Do We Stand?Semantic proximity Read ↗

Gene therapy for severe combined immunodeficiency: are we there yet?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.