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Advances in the application of CRISPR-Cas technology in rapid detection of pathogen nucleic acid

21 Sept 2023

Abstract excerpt

(Cas) are widely used as gene editing tools in biology, microbiology, and other fields. CRISPR is composed of highly conserved repetitive sequences and spacer sequences in tandem. The spacer sequence has homology with foreign nucleic acids such as viruses and plasmids; Cas effector proteins have endonucleases, and become a hotspot in the field of molecular diagnosis because they recognize and cut specific DNA or...

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PMID: 37808520
DOI: 10.3389/fmolb.2023.1260883

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