Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

FBXW4 Is Highly Expressed and Associated With Poor Survival in Acute Myeloid Leukemia

27 Feb 2020

Abstract excerpt

The F-box and WD repeat domain-containing (FBXW) proteins play an important role in ubiquitin proteasome by inducing protein degradation. Ten FBXW proteins have been identified in humans. The functions of FBXW proteins, like FBXW7, have been well established in many human cancers. However, little is known about their transcriptional expression profiles and relationship with prognosis in Acute Myeloid Leukemia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Multiple Myeloma Research and Treatments
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32175272
DOI: 10.3389/fonc.2020.00149

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 20 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

FBXW4 Is Highly Expressed and Associated With Poor Survival in Acute Myeloid LeukemiaPMID 32175272Read ↗

Pivotal Role of FBXW4 in Glioma Progression and Prognosis.Semantic proximity Read ↗

Comprehensive Gene Expression Analysis Reveals Factors that Influence the Progression, Occurrence and Development of AML-M4Semantic proximity Read ↗

E2F4 functions as a tumour suppressor in acute myeloid leukaemia via inhibition of the MAPK signalling pathway by binding to EZH2Semantic proximity Read ↗

Microarray-based analysis and clinical validation identify ubiquitin-conjugating enzyme E2E1 (UBE2E1) as a prognostic factor in acute myeloid leukemiaSemantic proximity Read ↗

Molecular insights and clinical implications for the tumor suppressor role of SCFFBXW7 E3 ubiquitin ligaseSemantic proximity Read ↗

Alternative splicing events show high prognostic values and indicate potential core genes in acute myeloid leukemiaSemantic proximity Read ↗

ALOX5AP is a new prognostic indicator in acute myeloid leukemiaSemantic proximity Read ↗

Integrated analysis reveals distinct molecular, clinical, and immunological features of B7-H3 in acute myeloid leukemia.Semantic proximity Read ↗

FBXO21 mediated degradation of p85α regulates proliferation and survival of acute myeloid leukemiaSemantic proximity Read ↗

Comprehensive characterization of FBXW7 mutational and clinicopathological profiles in human colorectal cancersSemantic proximity Read ↗

FBXW7β isoform drives transcriptional activation of a proinflammatory TNF cluster in normal and malignant pro-B cellsSemantic proximity Read ↗

Low Expression of Iron–Sulfur Cluster Binding Protein RFESD Predicts Adverse Clinic Outcomes in Acute Myeloid LeukemiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.