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Article

Amygdala-Based Altered miRNome and Epigenetic Contribution of miR-128-3p in Conferring Susceptibility to Depression-Like Behavior via Wnt Signaling.

The international journal of neuropsychopharmacology - 21 Apr 2020

Roy Bhaskar, Dunbar Michael, Agrawal Juhee, Allen Lauren, Dwivedi Yogesh

Abstract excerpt

BACKGROUND: Recent studies suggest that microRNAs (miRNAs) can participate in depression pathogenesis by altering a host of genes that are critical in corticolimbic functioning. The present study focuses on examining whether alterations in the miRNA network in the amygdala are associated with susceptibility or resiliency to develop depression-like behavior in rats. METHODS: Amygdala-specific altered miRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32173733
DOI: 10.1093/ijnp/pyz071
PMCID: PMC7171932

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