Article
Gilteritinib in Isolated Breast Relapse of FLT3 Positive Acute Myeloid Leukemia: A Case Report and Review of Literature.
Acta haematologica - 1 Jan 2022
Arrigo Giulia, D'Ardìa Stefano, Audisio Ernesta, Cerrano Marco, Freilone Roberto, Giai Valentina, Secreto Carolina, Urbino Irene, Frairia Chiara
Abstract excerpt
Extramedullary relapse of acute myeloid leukemia (AML) is not a rare event, and the FMS-like tyrosine kinase 3 (FLT3) mutation is a well-known risk factor. Gilteritinib is approved for relapsed/refractory FLT3+ AML, but its efficacy in extramedullary relapse is still undefined. Here, we present the case of a 69-year-old woman with therapy-related nucleophosmin-1 and FLT3-internal tandem duplication (FLT3-ITD)...
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