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Article

Novel Therapies in Chronic Lymphocytic Leukemia: A Rapidly Changing Landscape.

Current treatment options in oncology - 13 Mar 2020

Iovino Lorenzo, Shadman Mazyar

Abstract excerpt

OPINION STATEMENT: Treatment landscape of chronic lymphocytic leukemia (CLL) has changed since 2014 after the introduction of inhibitors of B-cell receptor signaling pathway (ibrutinib, acalabrutinib, idelalisib and duvelisib) and the inhibitor of the anti-apoptotic protein BCL-2 (venetoclax). In 2019, novel agents were upgraded from being a "great treatment option" to the "preferred choice" for all lines of...

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PMID: 32170458
DOI: 10.1007/s11864-020-0715-5

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