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Article

The prognostic value of tumor mutational burden and immune cell infiltration in esophageal cancer patients with or without radiotherapy.

Aging - 12 Mar 2020

Yuan Cheng, Xiang Liyang, Cao Kuo, Zhang Jianguo, Luo Yuan, Sun Wenjie, Zhang Nannan, Ren Jiangbo, Zhang Junhong, Gong Yan, Xie Conghua

Abstract excerpt

Growing evidence highlighted the tumor mutational burden (TMB) as an important feature of carcinogenesis and therapeutic efficacy in esophageal cancer (EC). Our study aimed to explore the genomic landscape and the correlation between TMB and immune cell infiltration in EC patients with or without radiotherapy. The EC patients were categorized into high TMB (TMB-H) and low TMB (TMB-L) groups by the ESTIMATE...

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Identifiers

PMID: 32165590
DOI: 10.18632/aging.102917
PMCID: PMC7093160

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