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Faecal virome transplantation decreases symptoms of type 2 diabetes and obesity in a murine model

12 Mar 2020

Abstract excerpt

OBJECTIVE: Development of obesity and type 2 diabetes (T2D) are associated with gut microbiota (GM) changes. The gut viral community is predominated by bacteriophages (phages), which are viruses that attack bacteria in a host-specific manner. The antagonistic behaviour of phages has the potential to alter the GM. As a proof-of-concept, we demonstrate the efficacy of faecal virome transplantation (FVT) from lean...

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PMID: 32165408
DOI: 10.1136/gutjnl-2019-320005

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