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Article

miR-25 Promotes Cardiomyocyte Proliferation by Targeting FBXW7

21 Jan 2020

Abstract excerpt

Induction of endogenous cardiomyocyte (CM) proliferation is one of the key strategies for heart regeneration. Increasing evidence points to the potential role of microRNAs (miRNAs) in the regulation of CM proliferation. Here, we used human embryonic stem cell (hESC)-derived CMs (hESC-CMs) as a tool to identify miRNAs that promote CM proliferation. We profiled miRNA expression at an early stage of CM...

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PMID: 32160702
DOI: 10.1016/j.omtn.2020.01.013

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