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Article

Cytochrome P450 metabolic resistance (CYP6P9a) to pyrethroids imposes a fitness cost in the major African malaria vector Anopheles funestus.

Heredity - 1 May 2020

Tchouakui Magellan, Riveron Miranda Jacob, Mugenzi Leon M J, Djonabaye Doumani, Wondji Murielle J, Tchoupo Micareme, Tchapga Williams, Njiokou Flobert, Wondji Charles S

Abstract excerpt

Metabolic resistance threatens the sustainability of pyrethroid-based malaria control interventions. Elucidating the fitness cost and potential reversal of metabolic resistance is crucial to design suitable resistance management strategies. Here, we deciphered the fitness cost associated with the CYP6P9a (P450-mediated metabolic resistance) in the major African malaria vector Anopheles funestus. Reciprocal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32157181
DOI: 10.1038/s41437-020-0304-1
PMCID: PMC7171194

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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