Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and Apoptosis

9 Mar 2020

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease for which the pathophysiological mechanisms of motor neuron loss are not precisely clarified. Environmental and epigenetic mechanisms such as microRNAs (miRNAs) could have a role in disease progression. We studied the expression pattern of miRNAs in ALS serum from 60 patients and 29 healthy controls. We also analyzed how deregulated miRNAs found...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amyotrophic Lateral Sclerosis Research
Share to Autophagy in Disease and Therapy
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32152380
DOI: 10.1038/s41598-020-61246-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Downregulation of miR-335-5P in Amyotrophic Lateral Sclerosis Can Contribute to Neuronal Mitochondrial Dysfunction and ApoptosisPMID 32152380Read ↗

Insights into the identification of a molecular signature for amyotrophic lateral sclerosis exploiting integrated microRNA profiling of iPSC-derived motor neurons and exosomesSemantic proximity Read ↗

Upregulated miR-10b-5p as a potential miRNA signature in amyotrophic lateral sclerosis patientsSemantic proximity Read ↗

Differential Expression of miRNAs in Amyotrophic Lateral Sclerosis PatientsSemantic proximity Read ↗

MicroRNA expression analysis identifies a subset of downregulated miRNAs in ALS motor neuron progenitorsSemantic proximity Read ↗

MicroRNAs: newcomers into the ALS picture.Semantic proximity Read ↗

Serum miRNAs miR-206, 143-3p and 374b-5p as potential biomarkers for amyotrophic lateral sclerosis (ALS)Semantic proximity Read ↗

Implications of miRNAs dysregulation in amyotrophic lateral sclerosis: Challenging for clinical applicationsSemantic proximity Read ↗

Wide-Ranging Analysis of MicroRNA Profiles in Sporadic Amyotrophic Lateral Sclerosis Using Next-Generation SequencingSemantic proximity Read ↗

MicroRNA Metabolism and Dysregulation in Amyotrophic Lateral Sclerosis.Semantic proximity Read ↗

Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral SclerosisSemantic proximity Read ↗

The Biogenesis of miRNAs and Their Role in the Development of Amyotrophic Lateral SclerosisSemantic proximity Read ↗

Small RNA Sequencing of Sporadic Amyotrophic Lateral Sclerosis Cerebrospinal Fluid Reveals Differentially Expressed miRNAs Related to Neural and Glial ActivitySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.