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Article

MAPK7 variants related to prognosis and chemotherapy response in osteosarcoma.

Annals of diagnostic pathology - 1 Jun 2020

Tesser-Gamba Francine, Paolillo Alini Trujillo, Del Giúdice Paniago Mario, Petrilli Antonio Sergio, Seixas Alves Maria Teresa, Garcia Filho Reynaldo Jesus, Toledo Sílvia Regina Caminada

Abstract excerpt

Osteosarcoma (OS) is a class of cancer originating from the bone, affecting mainly children and young adults. Our previous study showed that MAPK7 gene overexpression was significantly associated with tumor progression, poor treatment response, and worse overall survival, suggesting that MAPK7 could play an important role in OS tumorigenesis. We have investigated if MAPK7 overexpression was a result of any...

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PMID: 32145682
DOI: 10.1016/j.anndiagpath.2020.151482

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