Article
Murine dorsal hair type is genetically determined by polymorphisms in candidate genes that influence BMP and WNT signalling.
Experimental dermatology - 1 May 2020
Villani Rehan M, Johnson Ayaka, Galbraith Jack A, Baz Betoul, Handoko Herlina Y, Walker Graeme J, Khosrotehrani Kiarash
Abstract excerpt
Mouse dorsal coat hair types, guard, awl, auchene and zigzag, develop in three consecutive waves. To date, it is unclear if these hair types are determined genetically through expression of specific factors or can change based on their mesenchymal environment. We undertook a novel approach to this question by studying individual hair type in 67 Collaborative Cross (CC) mouse lines and found significant variation...
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