Article
LncRNA DLX6-AS1 increases the expression of HIF-1α and promotes the malignant phenotypes of nasopharyngeal carcinoma cells via targeting MiR-199a-5p.
Molecular genetics & genomic medicine - 1 Jan 2020
Yang Bin, Jia Lin, Ren Hui, Jin Caibao, Ren Qingrong, Zhang Haiyuan, Hu Desheng, Zhang Hao, Hu Liu, Xie Tao
Abstract excerpt
OBJECTIVE: To investigate the expression of long-chain noncoding growth stasis specific protein 6 antisense RNA1 (lncRNA DLX6-AS1) in nasopharyngeal carcinoma (NPC) tissues and cells, and its regulatory effect on malignant phenotypes of NPC cells. METHODS: The expressions of DLX6-AS1, miR-199a-5p, and HIF-1α mRNA in NPC issues and cells were detected by qRT-PCR. The proliferation, metastasis, and invasion of...
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