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Long non-coding RNA HUMT hypomethylation promotes lymphangiogenesis and metastasis via activating FOXK1 transcription in triple-negative breast cancer

5 Mar 2020

Abstract excerpt

BACKGROUND: Triple-negative breast cancer (TNBC) is the most malignant subtype of breast cancer with highly invasive ability and metastatic nature to the lymph nodes. Long non-coding RNAs (lncRNAs) have been widely explored in cancer tumorigenesis and progression. However, their roles in TNBC lymph node metastasis remains rarely studied. METHODS: The expression of lncRNA highly upregulated in metastatic TNBC...

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PMID: 32138762
DOI: 10.1186/s13045-020-00852-y

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