Article
The Effects of Graded Levels of Calorie Restriction XV: Phase Space Attractors Reveal Distinct Behavioral Phenotypes.
The journals of gerontology. Series A, Biological sciences and medical sciences - 17 Apr 2020
Sun Deshun, Liu Fei, Mitchell Sharon E, Ma Huanfei, Derous Davina, Wang Yingchun, Han Jackie J D, Promislow Daniel E L, Lusseau David, Douglas Alex, Speakman John R, Chen Luonan
Abstract excerpt
Calorie restriction (CR) has a positive impact on health and life span. Previous work, however, does not reveal the whole underlying mechanism of behavioral phenotypes under CR. We propose a new approach based on phase space reconstruction (PSR) to analyze the behavioral responses of mice to graded CR. This involved reconstructing high-dimensional attractors which topologically represent the intrinsic dynamics of...
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