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Article

Integration of single nucleotide variants and whole-genome DNA methylation profiles for classification of rheumatoid arthritis cases from controls.

Heredity - 1 May 2020

Amiri Roudbar Mahmoud, Mohammadabadi Mohammad Reza, Ayatollahi Mehrgardi Ahmad, Abdollahi-Arpanahi Rostam, Momen Mehdi, Morota Gota, Brito Lopes Fernando, Gianola Daniel, Rosa Guilherme J M

Abstract excerpt

This study evaluated the use of multiomics data for classification accuracy of rheumatoid arthritis (RA). Three approaches were used and compared in terms of prediction accuracy: (1) whole-genome prediction (WGP) using SNP marker information only, (2) whole-methylome prediction (WMP) using methylation profiles only, and (3) whole-genome/methylome prediction (WGMP) with combining both omics layers. The number of...

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Identifiers

PMID: 32127659
DOI: 10.1038/s41437-020-0301-4
PMCID: PMC7171157

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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