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Distinct gene expression patterns in vector-residing Leishmania infantum identify parasite stage-enriched markers

3 Mar 2020

Abstract excerpt

BACKGROUND: Leishmaniasis is a vector-borne neglected disease. Inside the natural sand fly vector, the promastigote forms of Leishmania undergo a series of extracellular developmental stages to reach the infectious stage, the metacyclic promastigote. There is limited information regarding the expression profile of L. infantum developmental stages inside the sand fly vector, and molecular markers that can...

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PMID: 32126078
DOI: 10.1371/journal.pntd.0008014

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