Article
Identification of runs of homozygosity affecting female fertility and milk production traits in Finnish Ayrshire cattle.
Scientific reports - 2 Mar 2020
Martikainen K, Koivula M, Uimari P
Abstract excerpt
Inbreeding gives rise to continuous lengths of homozygous genotypes called runs of homozygosity (ROH) that occur when identical haplotypes are inherited from both parents. ROHs are enriched for deleterious recessive alleles and can therefore be linked to inbreeding depression, defined as decreased phenotypic performance of the animals. However, not all ROHs within a region are expected to have harmful effects on...
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