Article
The Influence of Recombinational Processes to Induce Dormancy in Trypanosoma cruzi.
Frontiers in cellular and infection microbiology - 1 Jan 2020
Resende Bruno Carvalho, Oliveira Anny Carolline Silva, Guañabens Anna Carolina Paganini, Repolês Bruno Marçal, Santana Verônica, Hiraiwa Priscila Mazzochi, Pena Sérgio Danilo Junho, Franco Glória Regina, Macedo Andrea Mara, Tahara Erich Birelli, Fragoso Stênio Perdigão, Andrade Luciana Oliveira, Machado Carlos Renato
Abstract excerpt
The protozoan Trypanosoma cruzi is the causative agent of Chagas disease, a neglected tropical disease that affects around 8 million people worldwide. Chagas disease can be divided into two stages: an acute stage with high parasitemia followed by a low parasitemia chronic stage. Recently, the importance of dormancy concerning drug resistance in T. cruzi amastigotes has been shown. Here, we quantify the percentage...
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