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Classification of primary liver cancer with immunosuppression mechanisms and correlation with genomic alterations

26 Feb 2020

Abstract excerpt

BACKGROUND: The tumor microenvironment can be classified into immunologically active "inflamed" tumors and inactive "non-inflamed" tumors based on the infiltration of cytotoxic immune cells. Previous studies on liver cancer have reported a superior prognosis for inflamed tumors compared to non-inflamed tumors. However, liver cancer is highly heterogeneous immunologically and genetically, and a finer...

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PMID: 32113157
DOI: 10.1016/j.ebiom.2020.102659

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