Article
Identification of an Immune-specific Class of Hepatocellular Carcinoma, Based on Molecular Features.
Gastroenterology - 1 Sept 2017
Sia Daniela, Jiao Yang, Martinez-Quetglas Iris, Kuchuk Olga, Villacorta-Martin Carlos, Castro de Moura Manuel, Putra Juan, Camprecios Genis, Bassaganyas Laia, Akers Nicholas, Losic Bojan, Waxman Samuel, Thung Swan N, Mazzaferro Vincenzo, Esteller Manel, Friedman Scott L, Schwartz Myron, Villanueva Augusto, Llovet Josep M
Abstract excerpt
BACKGROUND & AIMS: Agents that induce an immune response against tumors by altering T-cell regulation have increased survival times of patients with advanced-stage tumors, such as melanoma or lung cancer. We aimed to characterize molecular features of immune cells that infiltrate hepatocellular carcinomas (HCCs) to determine whether these types of agents might be effective against liver tumors. METHODS: We...
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