Article
Bioinformatics analysis and genetic polymorphisms in genomic region of the bovine SH2B2 gene and their associations with molecular breeding for body size traits in qinchuan beef cattle.
Bioscience reports - 27 Mar 2020
Raza Sayed Haidar Abbas, Khan Rajwali, Gui Linsheng, Schreurs Nicola M, Wang Xiaoyu, Mei Chugang, Yang Xinran, Gong Cheng, Zan Linsen
Abstract excerpt
The Src homology 2 B 2 (SH2B2) gene regulate energy balance and body weight at least partially by enhancing Janus kinase-2 (JAK2)-mediated cytokine signaling, including leptin and/or GH signaling. Leptin is an adipose hormone that controls body weight. The objective of the present study is to evaluate the association between body measurement traits and SH2B2 gene polymorphisms as responsible mutations. For this...
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