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Article

Genetic Variants in STAT3 Promoter Regions and Their Application in Molecular Breeding for Body Size Traits in Qinchuan Cattle.

International journal of molecular sciences - 29 Mar 2018

Wu Sen, Wang Yaning, Ning Yue, Guo Hongfang, Wang Xiaoyu, Zhang Le, Khan Rajwali, Cheng Gong, Wang Hongbao, Zan Linsen

Abstract excerpt

Signal transducer and activator of transcription 3 (STAT3) plays a critical role in leptin-mediated regulation of energy metabolism. This study investigated genetic variation in STAT3 promoter regions and verified their contribution to bovine body size traits. We first estimated the degree of conservation in STAT3, followed by measurements of its mRNA expression during fetal and adult stages of Qinchuan cattle....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Shuffling

Share to Gene Expression Regulation

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Source

Open in PubMed Open full text

Identifiers

PMID: 29596388
DOI: 10.3390/ijms19041035
PMCID: PMC5979584

Genes

STAT3

Provenance

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