Article
Effect of genetic variations within the SH2B2 gene on the growth of Chinese cattle.
Gene - 10 Oct 2013
Yang Mingjuan, Fu Junhui, Lan Xianyong, Sun Yujia, Lei Chuzhao, Zhang Chunlei, Chen Hong
Abstract excerpt
As an adaptor protein, apart from potentiating Janus kinase 2 (JAK2) activation and promoting the insulin signaling pathway, Src homology 2 B 2 (SH2B2) indirectly takes part in the regulation of glucose uptake through the c-Cb1/CAP/TC10 pathway, which can in turn affect growth. In this study, we identified a 4bp indel mutation and three single nucleotide polymorphisms (SNPs) within the SH2B2 gene in 959...
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