Article
Graves' disease: Epidemiology, genetic and environmental risk factors and viruses.
Best practice & research. Clinical endocrinology & metabolism - 1 Jan 2020
Antonelli Alessandro, Ferrari Silvia Martina, Ragusa Francesca, Elia Giusy, Paparo Sabrina Rosaria, Ruffilli Ilaria, Patrizio Armando, Giusti Claudia, Gonnella Debora, Cristaudo Alfonso, Foddis Rudy, Shoenfeld Yehuda, Fallahi Poupak
Abstract excerpt
Graves' disease (GD) is the most common cause of hyperthyroidism in developed Countries. It is more common between 30 and 60 years; 5-10 times more frequent in women. The genetic predisposition accounts for 79% of the risk for GD, while environmental factors for 21%. About 70% of genes associated with autoimmune thyroid disorders (AITD) are implicated in T-cell function. Among GD endogenous factors, estrogens,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.