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Article

Infections, genetic and environmental factors in pathogenesis of autoimmune thyroid diseases.

Microbial pathogenesis - 1 Mar 2018

Shukla Sanjeev Kumar, Singh Govind, Ahmad Shahzad, Pant Prabhat

Abstract excerpt

In Autoimmune disease a combination of infection, genetic and environmental factors causes an autoimmune response to the thyroid gland (characterized by lymphocytic infiltrations), thyroid stimulating hormone receptor (TSHR) and different thyroid antigens. Graves' and Hashimoto disease are autoimmune disorders with genetic predisposition. CD40 that stimulates the proliferation and differentiation of lymphocytes...

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Source

Identifiers

PMID: 29325864
DOI: 10.1016/j.micpath.2018.01.004

Genes

PTPN22
TSHR

Provenance

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