Article
A Point Mutation in carR Is Involved in the Emergence of Polymyxin B-Sensitive Vibrio cholerae O1 El Tor Biotype by Influencing Gene Transcription.
Infection and immunity - 20 Apr 2020
Samanta Prosenjit, Mandal Rahul Shubhra, Saha Rudra Narayan, Shaw Sreeja, Ghosh Priyanka, Dutta Shanta, Ghosh Amit, Imamura Daisuke, Morita Masatomo, Ohnishi Makoto, Ramamurthy Thandavarayan, Mukhopadhyay Asish Kumar
Abstract excerpt
Antimicrobial peptides play an important role in host defense against Vibrio cholerae Generally, the V. cholerae O1 classical biotype is polymyxin B (PB) sensitive and El Tor is relatively resistant. Detection of classical biotype traits like the production of classical cholera toxin and PB sensitivity in El Tor strains has been reported in recent years, including in the devastating Yemen cholera outbreak during...
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