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Evaluation of Plasmodium vivax HAP2 as a transmission-blocking vaccine candidate

21 Feb 2020

Abstract excerpt

Transmission-blocking vaccine (TBV) is a promising strategy to interfere with the transmission of malaria. To date, only limited TBV candidate antigens have been identified for Plasmodium vivax. HAP2 is a gamete membrane fusion protein, with homology to the class II viral fusion proteins. Herein we reported the characterization of the PvHAP2 for its potential as a TBV candidate for P. vivax. The HAP2/GCS1 domain...

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PMID: 32093983
DOI: 10.1016/j.vaccine.2020.02.011

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